
bioGenous Biotechnology, Inc. is deeply committed to advancing foundational technological innovations in the organoid industry. It possesses globally leading, self-developed intellectual property in organoids and disease models, along with a GMP pharmaceutical-grade production technology system. Its main products include organoid culture reagents covering 23 types of normal tissues and 18 types of tumors, intelligent scenario-based equipment supporting the whole process of organoid construction, culture, and detection across multiple stages, and a flexible CRDMO technology platform tailored for pharmaceutical clients. Upholding the corporate vision of "Pioneering Pharmaceutical Innovation, Sharing Model Value," bioGenous is dedicated to providing standardized, pharmaceutical-grade upstream organoid solutions for the global biopharmaceutical industry. To date, it has served over 500 advanced international and domestic innovative pharmaceutical companies, research institutions, and medical organizations. Its products are exported to Europe and the United States, with cumulative sales exceeding one billion units.
The group's headquarters is located in Yangpu District, Shanghai, with R&D centers in Shanghai, Hong Kong, and Cambridge, UK. It has established branches and subsidiaries in multiple cities, including Beijing, Guangzhou, Wuhan, Nanjing, Suzhou (technical service base), Dezhou (northern production base), Nanchang, and Tianjin. The company has received strategic investments from AstraZeneca and the SDIC Fund.
Today, leveraging deep organoid resource development and AI data modeling, bioGenous is emerging as a leading enterprise driving the transition of innovative model methodologies from research-grade breakthroughs to pharmaceutical-grade applications.

To be a global pioneer in organoid model platforms

Pioneer Pharma Innovation, Democratize Model Value

Resilience Integrity Focus Responsibility

The founding team successfully constructed intestinal organoids at Tsinghua University.
The founding team applied organoid technology in a paper published in the journal Nature Communications.
Establishing normal and tumor organoid cultures for endodermal organs, achieving industrial translation.
Organregen® GMP-Grade, Stable Strain Growth Factor Pipeline Established, Comprehensively Advancing Organoid Research. bioGenous™ Organoid Multi-Cancer, Whole-Process Kits Now Available
In March 2020, the team successfully constructed the worlds first human-derived organoid model of SARS-CoV-2 infection, which was featured in an interview by Nature and highlighted on its homepage.
Collaborating with leading domestic companies in specialized segments of the innovative drug industry to create successful cases of new drug R&D and non-clinical evaluation systems using organoids.

An organoid is a 3D structure formed by culturing adult stem cells or pluripotent stem cells in vitro, which resembles the tissue from which it is derived. Organoids are highly consistent with their source tissues in terms of tissue structure, cell types, self-renewal capacity, and function. As such, they demonstrate unique advantages in various fields of biomedicine, including developmental biology, disease modeling, precision medicine, drug R&D, gene and cell therapies, infection and immunity, and regenerative medicine.

| Cell line | Caenorhabditis elegans | Drosophila melanogaster | Danio rerio | mouse model | PDX model | human-derived organoids | |
| ease of establishment | √ / × | √ | √ | √ | √ | √ | √ |
| ease of maintainence | √ | √ | √ | √ | √ | √ | √ |
| developmental simulation | × | √ | √ | √ | √ | × | √ |
| experimental cycle | √ | √ | √ | √ | √ | √ | √ |
| gene manipulation | √ | √ | √ | √ | √ | × | √ |
| genome-wide screening | √ | √ | √ | √ | × | × | √ |
| physiological complexity | × | √ | √ | √ | √ | √ | √ |
| experimental cost | √ | √ | √ | √ | √ | √ | √ |
| simulating the human body | √ | √ | √ | √ | √ | √ | √ |
| best √ good √ partially suitable √ unsuitable × | |||||||